Optimal health is determined by many factors that go beyond access to quality health care. As a result, hospitals in the U.S. have started to address the immediate social needs of their patients (such as food access or safe housing). This case series describes two Critical Access Hospital (CAH)-based initiatives addressing social needs at Lakewood Hospital in Staples, Minnesota and Northeastern Vermont Regional Hospital in St. Johnsbury, Vermont. The goal of the case series is to provide best practices for CAHs and communities that may wish to emulate these programs.